Developing Story: What Biomarkers Tell Us with Dr. Neil Vasan

Your medical records are full of letters and numbers—BRCA, PIK3CA, ESR1, PD-L1—but what do they really mean? These are biomarkers, and cracking their code could change your treatment and your prognosis.

In this episode, Dr. Neil Vasan breaks down the difference between prognostic biomarkers (how aggressive your cancer is) and predictive biomarkers (which treatments will work for you). Learn which biomarkers matter most for metastatic breast cancer, how germline mutations like BRCA and PALB2 open the door to targeted therapies like PARP inhibitors, and why somatic mutations like PIK3CA and ESR1 are reshaping treatment options in real time.