Front Row Seat: Can We Talk about the Cure? A Conversation with Dr. Eric Winer

Front Row Seat: Can We Talk about the Cure? A Conversation with Dr. Eric Winer

For decades, stage IV meant managing the disease — not beating it. That story is beginning to change.

In this episode of Live from Stage IV, Victoria Goldberg sits down with Dr. Eric Winer — oncologist, director of the Yale Cancer Center, and former president of ASCO — to ask a question that once felt impossible: Can we cure metastatic breast cancer?

Dr. Winer walks through the landmark trials reshaping HER2-positive treatment, introduces the concept of "curative hope," and gets into what's hardest about ER-positive and triple-negative disease, cancer dormancy, the science of exercise, and bold new trial designs like SAFFO and HORIZON that are rewriting the playbook.

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Front Row Seat: We'll Never Cure Cancer Without AI, Say Steve Brown & Lisa Booth

Front Row Seat: We'll Never Cure Cancer Without AI, Say Steve Brown & Lisa Booth

When Steve Brown's doctors missed his rare blood cancer for months, he turned to AI for answers. The system he built spotted the warning signs immediately—the same lab results his physicians had dismissed.

Now, as CEO of CureWise, Steve and patient advocate Lisa Booth are pioneering a new approach to cancer care: using AI agents trained as specialist doctors to help patients navigate treatment options, find clinical trials, and advocate effectively with their oncologists.

"There's a gap between what's possible and what most people are getting," Steve explains. "Cancer isn't just one disease. Everybody has their own unique version of it."

Lisa, an 11-year metastatic breast cancer survivor, adds: "My oncologist sees 600 patients. CureWise empowers me to show up to that seven-minute appointment with the right questions already researched and the clinical trials already identified."

This conversation explores how AI is transforming patient empowerment—and why knowledge might just save your life.

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