Developing Story: CureWise Goes Live - The AI Platform Built by Cancer Patients, for Cancer Patients

Live from Stage 4 | Episode #021 | 03/24/2026 | Front Row Seat

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Guests

Steve Brown

 The Founder and CEO of CureWise, an AI-powered platform designed to help patients navigate cancer diagnosis and treatment. A Stanford-educated physicist and computer scientist, he launched the company following his own experience with a rare and aggressive blood cancer that went undiagnosed by specialists for nearly a year.

Professional Background

  • Digital Health Pioneer: Before CureWise, Brown co-founded Health Hero in the late 1990s, a pioneer in remote patient monitoring that was later sold to Bosch.

  • Healthcare Reform: His early work influenced language in the 2003 healthcare reform act regarding chronic care and remote monitoring.

Lisa Booth

 A patient advocate living with stage 4 metastatic breast cancer (MBC) based in Seattle, Washington. She is widely recognized for her use of innovative medical technology and her participation in clinical trials to manage her condition.

Medical History

  • Diagnosis: De novo Stage 4 oligo metastatic breast cancer (April 2015) Cancer Type: HER2 activating mutation Duration: Heading into 11-year anniversary

  • Clinical Trials: To treat her MBC, she has traveled across the country, participating in oncology clinical trials at institutions such as Sharp Memorial Hospital in San Diego and facilities in New York.

Advocacy and Innovation

  • AI in Healthcare: Booth was one of the first patients in the U.S. to use CureWise, an artificial intelligence application. The tool analyzes personal medical records and genomics data to identify specific clinical trials and treatment scenarios.

  • Public Speaking: She shares her story to provide hope to other patients and to emphasize the importance of patient-led research and clinical trial access.

Lynda Weatherby

A dedicated patient advocate living in Seattle, Washington, who has been diagnosed with metastatic breast cancer (MBC) since 2013. Originally diagnosed at age 36 with Stage 0 DCIS (a pre-cancer), she underwent a bilateral mastectomy; 12 years later, her cancer recurred and spread to her skeleton, brain, and a facial nerve (trigeminal nerve).

Lynda co-founded and co-chaired the Northwest MBC Conference from 2016 to 2020, hosted by Amazon, and serves on the Executive Committee of the Metastatic Breast Cancer Alliance and the Board of METAvivor. She is also a producer for the “Our MBC Life” podcast and supports the “Live from Stage 4” podcast.

A mother of two and a young mom when her cancer was first diagnosed, Lynda has become a leading voice for Postpartum Breast Cancer (PPBC), raising awareness about its higher risk of metastasis. She is passionate about making MBC survivable, especially for young women, mothers, and patients with brain metastases. Her work bridges industry, non-profits, and clinical organizations to elevate unmet needs in MBC.

Lynda remains deeply grateful for the care she received at Seattle Cancer Care Alliance and UW Medicine, and continues to advocate for research, awareness, and patient support in the MBC community.

Todd Weatherby

Chief Executive Officer (CEO) of Siemens Advanta, leading the company’s professional services and consultancy business as of March 1, 2024. Prior to this role, he served as Executive Advisor at TempoPay (July 2023–February 2024) and held multiple executive advisory positions at StreamNative, GeoFusion LLC, Eviden, and Near Summit Capital during the same period.

Before joining Siemens, Weatherby was the VP, AWS Professional Services Worldwide at Amazon Web Services (AWS), where he spent 10 years (2012–2022). He launched the AWS ProServe business in 2012 from a six-pager, expanded it to thousands of customers and employees across 60+ countries, and led hundreds of sales and delivery employees while managing $665 million in bookings over seven years. Earlier, he held leadership roles at Microsoft (16 years, 1995–2011), including General Manager of Product Management and Director of Customer and Partner Experience.

Weatherby spent 16 years at Microsoft before moving to AWS in 2012. He is also an Angel Investor at Alliance of Angels and an Executive Connector at Baufest. In his global role at Siemens Advanta, he is based in Germany and the United States, focusing on AI, cybersecurity, energy efficiency, and the Siemens Xcelerator digital platform.


Quick Summary

CureWise, an AI-powered health platform built by cancer patients for cancer patients, officially launched on June 20th. Founder Steve Brown (navigating his own rare cancer for over a year and a half) and co-founder Lisa Booth (11-year metastatic breast cancer survivor) joined Victoria Goldberg along with beta users Lynda and Todd Weatherby to walk through what the platform does, how it works, and why it matters. The conversation covers everything from connecting your medical records to preparing for your next oncology appointment, grounded in real patient and caregiver experiences.

Key Takeaways

1. Your medical records are already yours. You just need to connect them. The 2021 CARES Act gives every US patient the right to immediate electronic access to their records. CureWise uses this to pull your full history from multiple institutions into one place, automatically updated weekly.

2. Preparation changes outcomes. Steve used CureWise for an hour before his doctor's appointment and caught a mistake another doctor had made. Lisa sent her oncologist questions in advance and got a treatment decision she felt confident in. The platform is designed to help you rehearse before you walk in the room.

3. AI hallucination is a real risk. CureWise addresses it. The Cross-Check feature sends your question to ChatGPT, Claude, and Gemini simultaneously, then synthesizes where they agree and where they differ. It is a built-in second and third opinion.

4. 60% of cancer patients have an actionable mutation. Only 15% are being treated for it. That gap exists largely because patients don't know to ask. CureWise is designed to close it.

5. Caregivers are part of the equation. Todd's experience highlighted a gap in the current onboarding for caregivers, one Lisa confirmed is already on the near-term roadmap. For now, the support team can help navigate it.

6. It's not a doctor. It's a navigator. CureWise has strict guardrails. It will not diagnose or prescribe. It will explain, educate, and prepare, so the conversation with your actual physician is richer and more collaborative.

7-day free trial. $49/month or $36/month annually. Sign up at www.curewise.com.

The CureWise Origin Story

  • The Diagnostic Gap: After months of weight loss and fatigue, Brown’s symptoms were dismissed by physicians as "stress" or "gas".

  • The AI Breakthrough: Using his background in tech, Brown built an "AI swarm"—multiple agents with different perspectives—to analyze his medical records. Within minutes, the AI flagged signs of plasma cell dyscrasias, which led to a life-saving bone marrow biopsy.

  • Mission: He founded CureWise to ensure other patients have access to the same "precision medicine" and autonomous AI agents to review records and identify treatment options that clinicians might mis

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Developing Story: Beyond Camizestrant — The Evolving Landscape of ER+/HER2- MBC with Dr. Sarah Premji