Developing Story: CureWise Goes Live - The AI Platform Built by Cancer Patients, for Cancer Patients
You have ten minutes with your oncologist. Ten minutes to ask the right questions, understand what's happening inside your body, and make decisions that could change everything. For most cancer patients, that's not enough time — and nobody taught you how to prepare.
CureWise was built to change that. On June 20th, the AI platform created by cancer patients Steve Brown and Lisa Booth officially launched. On this episode of Live From Stage 4, we sit down with Steve, Lisa, and real beta users Lynda and Todd Weatherby to find out what it actually does, how it works, and why it matters.
Developing Story: Beyond Camizestrant — The Evolving Landscape of ER+/HER2- MBC with Dr. Sarah Premji
The oral SERD era has arrived, and the treatment landscape for HR+/HER2- metastatic breast cancer is changing fast. Hosts Victoria Goldberg and Abigail Johnston sit down with Dr. Sarah Premji of Sarah Cannon to map out what has shifted beyond SERENA-6, from new FDA approvals and emerging mechanisms to real-world sequencing decisions and the latest trial data. If you are trying to make sense of a rapidly evolving algorithm, this episode is for you.
Developing Story: The Camizestrant Vote, Doctors Weigh In with Dr. Sarah Sammons & Dr. Neil Vasan
When the ODAC voted 6–3 against the camizestrant strategy, the headlines told you what happened — this episode tells you why. We're back for round two with Dr. Sarah Sammons, newly appointed Co-Leader of Breast Oncology at the University of Maryland Greenebaum Comprehensive Cancer Center, and Dr. Neil Vasan, Acting Chair of the ODAC and Director of Translational Research in Breast Cancer at NYU Langone Health, who sat in that room and cast one of the three yes votes. Alongside patient advocates Janice Cowden and Abigail Johnston, we break down the four FDA critiques that drove the vote, what the quality of life data showed and why regulators couldn't act on it, and what the FDA's new August 14th review deadline means for patients. Plus: why this science isn't going anywhere, and what ctDNA-guided treatment could look like in the very near future.
Developing Story: The Camizestrant Vote — When Your Blood Test Knows Before Your Scan Does
Six MBC patient advocates join host Victoria Goldberg to break down the FDA advisory committee's vote on camizestrant and the SERENA-6 trial. The panel unpacks what the vote really means, whether the science of molecular progression is ready for clinical practice, and why patient advocates need a seat at the table before trials are designed.
Front Row Seat: Dr. Fatima Cardoso on Aiming Higher - Hope and the Road to a Cure
For decades, metastatic breast cancer meant one thing: managing the disease. But a new global report — and a bold new charter — say it's time to aim higher. Host Victoria Goldberg sits down with Dr. Fátima Cardoso of the ABC Global Alliance to examine 10 years of hard-won progress, confront the inequalities that have grown worse, and explore why, for the first time, the word cure is entering the conversation.
Front Row Seat: Can We Talk about the Cure? A Conversation with Dr. Eric Winer
For decades, stage IV meant managing the disease — not beating it. That story is beginning to change.
In this episode of Live from Stage IV, Victoria Goldberg sits down with Dr. Eric Winer — oncologist, director of the Yale Cancer Center, and former president of ASCO — to ask a question that once felt impossible: Can we cure metastatic breast cancer?
Dr. Winer walks through the landmark trials reshaping HER2-positive treatment, introduces the concept of "curative hope," and gets into what's hardest about ER-positive and triple-negative disease, cancer dormancy, the science of exercise, and bold new trial designs like SAFFO and HORIZON that are rewriting the playbook.
Thriving Together 2026: LBBC's MBC Conference Through Our Eyes
"You walk into a room full of people living with metastatic breast cancer and you just... break down. Not because it's sad — though it is — but because for the first time, you're not alone in it."
Twenty years in, LBBC's Thriving Together Conference is still doing what no other event in the MBC space does: bringing patients together not just to learn, but to find each other. In this episode, four MBC patients who attended the 2026 conference share what moved them, what the science is saying, and why they'll keep coming back.
Front Row Seat: The Enigma of the Blood-Brain Barrier & More with Dr. Nancy Lin
Dr. Nancy Lin of Dana-Farber Cancer Institute joins us to talk about one of the most complex challenges in metastatic breast cancer: when it spreads to the brain. She walks us through the newest treatments, the latest trial data, and the biology of the blood-brain barrier — why it blocks most drugs, and how researchers are finally learning to work around it.
Front Row Seat: We'll Never Cure Cancer Without AI, Say Steve Brown & Lisa Booth
When Steve Brown's doctors missed his rare blood cancer for months, he turned to AI for answers. The system he built spotted the warning signs immediately—the same lab results his physicians had dismissed.
Now, as CEO of CureWise, Steve and patient advocate Lisa Booth are pioneering a new approach to cancer care: using AI agents trained as specialist doctors to help patients navigate treatment options, find clinical trials, and advocate effectively with their oncologists.
"There's a gap between what's possible and what most people are getting," Steve explains. "Cancer isn't just one disease. Everybody has their own unique version of it."
Lisa, an 11-year metastatic breast cancer survivor, adds: "My oncologist sees 600 patients. CureWise empowers me to show up to that seven-minute appointment with the right questions already researched and the clinical trials already identified."
This conversation explores how AI is transforming patient empowerment—and why knowledge might just save your life.
Live Chat: The Courage to Choose Life on Your Terms with Dar Finkelstein
"One of my MBC friends said to me, 'You're feeling guilty about making people cry, but you've instilled in them so much joy and what they're doing, what you're seeing is them sharing the joy back to you.' And she said, 'It looks like tears, but that's their love coming back to you.'"
—Dar Finkelstein on accepting loved ones' grief
Podcasters Roundtable: Change Your One Thing with Gary Thompson
We don't have to change everything. We just have to change our one thing. And if we each indeed change our one thing, then we will have changed everything. My ideal audience is someone looking for their one thing and realizing that whatever it is, whenever they find it, to just follow their heart, follow their passion, and go for it. We as an individual person have the capacity to create great change. Love is neither big nor small. It's always enough
Live Chat: From Devastating Diagnosis to Distinction with Lesley Stephen MBE
Imagine this: You're a mother of four. You think you have a chest infection, but it turns out to be stage four metastatic breast cancer—in your lungs, liver, and bones. The nurse sitting across from you has tears in her eyes. You're given one, maybe two years to live. Treatment after treatment fails. Finally, your doctor says the words no one wants to hear: "You need to get your affairs in order."
So you take your kids to New York for one last family vacation.
But when you come home, there's one spot left on a clinical trial in Glasgow. You take it. And against all odds, it saves your life—for seven years.
That's the beginning of Lesley Stephen's story. Twelve years later, she's not only alive and cancer-free—she's just been honored by the British Royal Family with an MBE. Princess Anne herself presented Leslie with her medal at Windsor Castle for her extraordinary work transforming how metastatic breast cancer patients access clinical trials and cutting-edge care.
Our Happy Place: Heated Rivalry Rx
Victoria and Jill discuss their obsession with HBO Max's "Heated Rivalry," exploring why this hockey romance has become the perfect escape from MBC realities. Victoria shares personal insights as a Russian speaker, and the hosts draw parallels between sports teams and their community. Spoilers included!
Podcasters Roundtable: Melissa Berry on Fashion Meets Cancer Advocacy
Melissa Berry, founder of Cancer Fashionista and host of "Dear Cancer, I'm Beautiful," joins us to discuss building beauty and wellness resources for cancer patients. From her background as a fashion publicist to creating an evergreen podcast library, Melissa shares why looking like yourself matters, how she selects topics, and what keeps her connected to advocacy. We explore inclusive language for metastatic patients, financial toxicity, intimacy after cancer, and the power of podcasting as a tool for community building.
Front Row: SABCS 2025 Insights with Dr. Francisco Esteva
Join host Victoria Goldberg and Dr. Francisco Esteva as they break down the groundbreaking research from the San Antonio Breast Cancer Symposium 2025. Discover the latest advances in metastatic breast cancer treatment, including new first-line therapies for HER2-positive disease with 40-month progression-free survival, oral SERDs revolutionizing hormone receptor-positive treatment, and antibody drug conjugates transforming triple-negative breast cancer care. Dr. Esteva shares expert insights on brain metastasis prevention, liquid biopsy-guided therapy switching, and how artificial intelligence is reshaping oncology. Whether you're a patient, caregiver, or healthcare professional, this episode offers hope and practical information about the cutting-edge treatments available in 2026.
Future at Risk: Why We Can’t Turn Back Now with Josh Newby
In this episode, co-hosts Victoria Goldberg and Martha Carlso are joined by Josh Newby, Founder and Executive Director of Theresa’s Research Foundation (TRF), for an in-depth conversation about the evolving landscape of metastatic breast cancer research and advocacy. Josh shares the origins and mission of his foundation, the challenges faced in funding and organizing medical conferences, and the shift toward curative approaches for metastatic breast cancer. The discussion covers the impact of recent funding cuts, the importance of collaboration among institutions and industry partners, and the critical role of patient advocates. The group also explores the realities of grant funding, the effects of political and economic changes on research, and the need for credible information and community support for patients. Throughout, the conversation highlights the resilience and determination required to push forward in the face of uncertainty, emphasizing the message: we can’t turn back now.
Live Chat: Shining a Light on MBC with Tami Bowling
When a life-changing diagnosis led Tami Bowling to advocacy, she fueled the movement to Light up MBC. In this episode, Tami shares her personal experience, the origins of LightUp MBC and LightUp MBC Live, and how lighting up landmarks is bringing hope, awareness, and vital research funding to the metastatic breast cancer community.
Future at Risk: A Researcher’s Story
Host Victoria Goldberg interviews scientist Na Zhao about the personal and professional fallout from NIH budget cuts, highlighting how these funding challenges threaten cancer research and the careers of young scientists. Na shares her own story of lost opportunities and the broader impact on the scientific community, while both guests stress the importance of advocacy and hope for a future where cancer becomes a manageable disease
Fighting for Patients: Dr. Rebecca Shatsky on Insurance, Burnout, and Hope in MBC
Dr. Rebecca Shatsky, Director of Breast Medical Oncology at UC San Diego, shares her experiences fighting for patients with breast cancer. In this episode, Dr. Shatsky discusses the growing challenges clinicians face—from insurance denials and funding cuts to the emotional toll of burnout and the spread of cancer misinformation.
Hear real stories about advocating for life-saving treatments, navigating the complexities of clinical trials, and the importance of patient empowerment. Dr. Shatsky also offers hope, highlighting the latest breakthroughs in metastatic breast cancer research and the progress being made in treatment options.
Whether you’re a patient, caregiver, or healthcare professional, this episode delivers candid insights, practical advice, and a message of resilience and hope in the face of adversity.
Podcasters Roundtable: Samira Daswani, Host of The Patient from Hell
In this episode, hosts Victoria Goldberg and Abigail Johnston sit down with Samira Daswani, host of "The Patient From Hell" podcast, for a candid and insightful conversation about patient advocacy, storytelling, and the evolving landscape of cancer care. Samira shares her path from reluctant podcast guest to passionate host, highlighting the importance of amplifying patient voices and democratizing information for those navigating cancer diagnoses—especially in communities where open discussion is rare.
The discussion delves into the challenges of reaching diverse audiences, the power of authentic, minimally edited conversations, and the need for both scientific and personal perspectives in patient-centered content. The trio reflects on the shifting attitudes in cancer communities, the critical role of support networks, and the ongoing mission to educate and empower patients worldwide. The episode wraps up with ideas for future collaborations and a shared commitment to making a meaningful impact through storytelling and advocacy.