Developing Story: How PCDI Is Changing the Way We Think About Dosing
What if the highest dose isn't the right dose? Victoria talks with the Patient-Centered Dosing Initiative team about two groundbreaking surveys revealing that lower doses of cancer drugs can be just as effective, while dramatically improving quality of life. Learn why patients are having dose reduction conversations with their doctors, what real-world data shows about side effects, and how you can advocate for personalized treatment.
Developing Story: From CLEOPATRA to Life on Enhertu – HER2+ MBC with Dr. Erika Hamilton & Dr. Sarah Premji
wenty-five years ago, HER2-positive breast cancer meant a two-year death sentence. Today, patients are living 12+ years on first-line treatment—and some are being cured.
In this deep dive, host Victoria Goldberg (living with metastatic HER2+ cancer for 12 years) and leading oncologists Dr. Erika Hamilton and Dr. Sarah Premji unpack the drugs, trials, and real-world strategies transforming one of cancer's most feared diagnoses into its greatest success story.
From CLEOPATRA's game-changing 16-month survival boost to antibody-drug conjugates that deliver chemotherapy straight to cancer cells, learn how precision medicine is rewriting the rules—and what patients need to know about side effects, sequencing, and hope.
Symptoms Spotlight: Chemo-Induced Nausea and Vomiting (CINV) with Abigail Johnston and Melanie Sisk
When nausea and vomiting is caused by a substance that you're taking like chemotherapy, your go-to remedies for addressing nausea and vomiting may not work as well. I had my bag of tricks that I would use, especially like during pregnancy—things I could smell or different pressure points—those kinds of things. But none of that worked when it came to chemotherapy-induced nausea and vomiting.
Symptoms Spotlight: Diarrhea with Abigail Johnston and Melanie Sisk
Melanie Sisk and Abigail Johnston discuss managing diarrhea from cancer medications—a common but often embarrassing side effect. Learn practical strategies for treatment, when to seek specialist help, and how to advocate for better quality of life during cancer treatment.
Symptoms Spotlight: Fatigue with Abigail Johnston and Melanie Sisk
Join hosts Melanie Sisk and Abigail Johnston as they shine a light on the real experiences of managing cancer symptoms. In each episode of the Symptoms Spotlight series of short episodes, we explore different symptoms caused by cancer or its treatment, sharing practical insights and hard-won wisdom directly from patients who've been there.
Melanie and Abigail share their experiences managing cancer-related fatigue over 5+ years of treatment. They discuss practical solutions including exercise programs like LiveStrong and Two Unstoppable, Medicare fitness benefits, medication options like Ritalin, and the importance of nutrition, hydration, and monitoring vitamin levels.
Front Row: SABCS 2025 Insights with Dr. Francisco Esteva
Join host Victoria Goldberg and Dr. Francisco Esteva as they break down the groundbreaking research from the San Antonio Breast Cancer Symposium 2025. Discover the latest advances in metastatic breast cancer treatment, including new first-line therapies for HER2-positive disease with 40-month progression-free survival, oral SERDs revolutionizing hormone receptor-positive treatment, and antibody drug conjugates transforming triple-negative breast cancer care. Dr. Esteva shares expert insights on brain metastasis prevention, liquid biopsy-guided therapy switching, and how artificial intelligence is reshaping oncology. Whether you're a patient, caregiver, or healthcare professional, this episode offers hope and practical information about the cutting-edge treatments available in 2026.